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  #46  
Old 09-22-2007, 03:48 PM
ironjustice
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Posts: n/a
Default Re: Testosterone Replacement and Health

- quote -

> > On Sep 22, 8:39 am, "Steve Young" <bowtieATbrightdslDOTnet> wrote: Also diabetes. This by an MD, much antidotal, but not without actual lab testing groups of patients (with some minimal controls):

http://www.lef.org/magazine/mag2007/...abetes_01.html <<

Iron causes endocrine problems .. and since diabetics have .. iron /
excess iron .. and since they are now using iron chelators in
osteoporosis .. ?
I would say evidence is leaning towards .. iron as the .. **causal**
factor .. IN .. both.

Or at the very least .. since they are targeting iron IN .. both .. ?


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk







  #45  
Old 09-22-2007, 03:39 PM
Steve Young
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Default Re: Testosterone Replacement and Health

"Ron Peterson" <ron[at]shell.core.com> wrote

- quote -

> On Sep 21, 5:46 pm, "ironjust...[at]aol.com" <ironjust...[at]aol.com> wrote:

> > Now since epo .. kills ya .. I suppose a hormone which ALSO ..
> > increases red blood cell count .. 'may' .. also .. kill ya .. ?


> Low testosterone may be a factor in osteoporosis.


Also diabetes. This by an MD, much antidotal, but not without actual lab
testing groups of patients (with some minimal controls):
<http://www.lef.org/magazine/mag2007/jul2007_report_diabetes_01.html>




  #44  
Old 09-22-2007, 03:39 PM
ironjustice
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Posts: n/a
Default Re: Testosterone Replacement and Health

- quote -

> > On Sep 22, 6:58 am, Ron Peterson <r...[at]shell.core.com> wrote: Low testosterone may be a factor in osteoporosis.
<<

"whereas castration reduced protein in the urine"

Guess what .. treatment .. 'they' have in store for .. ya ..

Cup em with BOTH hands ..

Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk






  #43  
Old 09-22-2007, 03:32 PM
MarilynMann
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Default Re: Testosterone Replacement and Health

On Sep 21, 8:46 pm, "ironjust...[at]aol.com" <ironjust...[at]aol.com> wrote:
- quote -

> Now since epo .. kills ya .. I suppose a hormone which ALSO ..
> increases red blood cell count .. 'may' .. also .. kill ya .. ?
>
> Yep ..
>
> Testosterone therapy may lead to more ills
> Rats given hormone showed higher blood pressure, signs of kidney
> trouble
>
> Updated: 3:52 p.m. PT Aug 14, 2007
> NEW YORK - Testosterone supplements may make aging men feel and look
> better, but the results of a study conducted in rats suggest that it
> could lead to kidney damage and worsen high blood pressure
> (hypertension).
>
> Testosterone levels gradually decrease with age in healthy men, a
> condition some doctors refer to as "andropause," which is analogous to
> menopause in women.
>
> A growing number of healthy older American men take testosterone
> replacement therapy to improve their feelings of well being, sex
> drive, and muscle mass.
>
> "Because chronic cardiovascular disease, like hypertension or kidney
> disease, is related to a sharp decrease in testosterone, a lot of
> doctors also prescribe testosterone to men who suffer from heart
> disease," Dr. Radu Iliescu, of University of Mississippi Medical
> Center, Jackson, noted in a telephone interview with Reuters Health.
>
> However, "no well-controlled clinical studies have addressed the
> effects of testosterone on the cardiovascular system," Iliescu warned,
> "and our research actually showed that testosterone contributes to
> hypertension and end-stage renal disease in various rodent
> experimental models."
>
> Iliescu and colleagues found that testosterone supplements caused
> about a twofold increase in testosterone levels in the blood of male
> rats. They also found that blood pressure was significantly higher in
> testosterone-supplemented rats compared with normal "control" rats.
> Castration did not alter blood pressure levels.
>
> Compared with normal rats, testosterone-supplemented rats also had
> higher concentrations of protein in the urine, a sign of possible
> kidney trouble, whereas castration reduced protein in the urine.
>
> These results were reported by Iliescu and co-researchers at a recent
> meeting of the American Physiological Society in Austin, Texas.
>
> Supplementing testosterone or preventing the testosterone loss that
> occurs with age or chronic disease may actually worsen preexisting
> heart or kidney disease, the researchers conclude.
>
> "We are trying to bring to the attention of the clinician of using
> care when prescribing testosterone supplements and to address
> cardiovascular risk," Iliescu told Reuters Health.
>


Even if low endogenous testosterone is associated with a certain
disease (e.g., heart disease), one cannot assume that (1) the
association is causal, or (2) exogenous testosterone will help prevent
that disease. You would have to do a RCT to test that proposition.
My impression is that this is an area where a lot is not known. I
note that there are also women who are prescribed low-dose
testosterone for sexual dysfunction. In my opinion, this practice is
also risky business. For one thing, high endogenous testosterone is
linked to breast cancer. One cannot assume that exogenous
testosterone would not have this association as well (I have not seen
any research on this).

The whole experience with HRT over the last 30 years should be
cautionary tale here.

Marilyn

  #42  
Old 09-22-2007, 02:37 PM
Alan
Guest
 
Posts: n/a
Default Re: Testosterone Replacement and Health



Ron Peterson wrote:
- quote -

> On Sep 21, 5:46 pm, "ironjust...[at]aol.com" <ironjust...[at]aol.com> wrote:
> > Now since epo .. kills ya .. I suppose a hormone which ALSO ..
> > increases red blood cell count .. 'may' .. also .. kill ya .. ?

>
> Low testosterone may be a factor in osteoporosis.
>
> --
> Ron
>
>


And high testosterone may be a factor in getting someone pregnant. :-)
  #41  
Old 09-22-2007, 01:58 PM
Ron Peterson
Guest
 
Posts: n/a
Default Re: Testosterone Replacement and Health

On Sep 21, 5:46 pm, "ironjust...[at]aol.com" <ironjust...[at]aol.com> wrote:
- quote -

> Now since epo .. kills ya .. I suppose a hormone which ALSO ..
> increases red blood cell count .. 'may' .. also .. kill ya .. ?


Low testosterone may be a factor in osteoporosis.

--
Ron


  #40  
Old 09-22-2007, 03:37 AM
trigonometry1972@gmail.com
Guest
 
Posts: n/a
Default Re: Testosterone Replacement and Health


ironjustice[at]aol.com wrote:
- quote -

> Now since epo .. kills ya .. I suppose a hormone which ALSO ..
> increases red blood cell count .. 'may' .. also .. kill ya .. ?
>
> Yep ..
>
> Testosterone therapy may lead to more ills
> Rats given hormone showed higher blood pressure, signs of kidney
> trouble
>
> Updated: 3:52 p.m. PT Aug 14, 2007
> NEW YORK - Testosterone supplements may make aging men feel and look
> better, but the results of a study conducted in rats suggest that it
> could lead to kidney damage and worsen high blood pressure
> (hypertension).
>
> Testosterone levels gradually decrease with age in healthy men, a
> condition some doctors refer to as "andropause," which is analogous to
> menopause in women.
>
> A growing number of healthy older American men take testosterone
> replacement therapy to improve their feelings of well being, sex
> drive, and muscle mass.
>
> "Because chronic cardiovascular disease, like hypertension or kidney
> disease, is related to a sharp decrease in testosterone, a lot of
> doctors also prescribe testosterone to men who suffer from heart
> disease," Dr. Radu Iliescu, of University of Mississippi Medical
> Center, Jackson, noted in a telephone interview with Reuters Health.
>
> However, "no well-controlled clinical studies have addressed the
> effects of testosterone on the cardiovascular system," Iliescu warned,
> "and our research actually showed that testosterone contributes to
> hypertension and end-stage renal disease in various rodent
> experimental models."
>
> Iliescu and colleagues found that testosterone supplements caused
> about a twofold increase in testosterone levels in the blood of male
> rats. They also found that blood pressure was significantly higher in
> testosterone-supplemented rats compared with normal "control" rats.
> Castration did not alter blood pressure levels.
>
> Compared with normal rats, testosterone-supplemented rats also had
> higher concentrations of protein in the urine, a sign of possible
> kidney trouble, whereas castration reduced protein in the urine.
>
> These results were reported by Iliescu and co-researchers at a recent
> meeting of the American Physiological Society in Austin, Texas.
>
> Supplementing testosterone or preventing the testosterone loss that
> occurs with age or chronic disease may actually worsen preexisting
> heart or kidney disease, the researchers conclude.
>
> "We are trying to bring to the attention of the clinician of using
> care when prescribing testosterone supplements and to address
> cardiovascular risk," Iliescu told Reuters Health.
>
> Copyright 2007 Reuters Limited. All rights reserved.
>
>
> Who loves ya.
> Tom
>
>
> Jesus Was A Vegetarian!
> http://jesuswasavegetarian.7h.com
>
>
> Man Is A Herbivore!
> http://tinyurl.com/a3cc3
>
>
> DEAD PEOPLE WALKING
> http://tinyurl.com/zk9fk



Well Tom this article is crud. And besides
if the hemocrit tends to go high as person
can have blood drawn off. Low testosterone
is related to heart failure according to at least some of the
evidence.
Moreover the devil is in the detail of both animal models
and treatment protocols. I sure you know about
the devil, Tom ;-)

  #39  
Old 09-22-2007, 12:46 AM
ironjustice@aol.com
Guest
 
Posts: n/a
Default Testosterone Replacement and Health

Now since epo .. kills ya .. I suppose a hormone which ALSO ..
increases red blood cell count .. 'may' .. also .. kill ya .. ?

Yep ..

Testosterone therapy may lead to more ills
Rats given hormone showed higher blood pressure, signs of kidney
trouble

Updated: 3:52 p.m. PT Aug 14, 2007
NEW YORK - Testosterone supplements may make aging men feel and look
better, but the results of a study conducted in rats suggest that it
could lead to kidney damage and worsen high blood pressure
(hypertension).

Testosterone levels gradually decrease with age in healthy men, a
condition some doctors refer to as "andropause," which is analogous to
menopause in women.

A growing number of healthy older American men take testosterone
replacement therapy to improve their feelings of well being, sex
drive, and muscle mass.

"Because chronic cardiovascular disease, like hypertension or kidney
disease, is related to a sharp decrease in testosterone, a lot of
doctors also prescribe testosterone to men who suffer from heart
disease," Dr. Radu Iliescu, of University of Mississippi Medical
Center, Jackson, noted in a telephone interview with Reuters Health.

However, "no well-controlled clinical studies have addressed the
effects of testosterone on the cardiovascular system," Iliescu warned,
"and our research actually showed that testosterone contributes to
hypertension and end-stage renal disease in various rodent
experimental models."

Iliescu and colleagues found that testosterone supplements caused
about a twofold increase in testosterone levels in the blood of male
rats. They also found that blood pressure was significantly higher in
testosterone-supplemented rats compared with normal "control" rats.
Castration did not alter blood pressure levels.

Compared with normal rats, testosterone-supplemented rats also had
higher concentrations of protein in the urine, a sign of possible
kidney trouble, whereas castration reduced protein in the urine.

These results were reported by Iliescu and co-researchers at a recent
meeting of the American Physiological Society in Austin, Texas.

Supplementing testosterone or preventing the testosterone loss that
occurs with age or chronic disease may actually worsen preexisting
heart or kidney disease, the researchers conclude.

"We are trying to bring to the attention of the clinician of using
care when prescribing testosterone supplements and to address
cardiovascular risk," Iliescu told Reuters Health.

Copyright 2007 Reuters Limited. All rights reserved.


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

 

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health, replacement, testosterone
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