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  #108  
Old 05-20-2008, 02:28 PM
Marshall Price
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

Andrew B. Chung, MD/PhD wrote:
- quote -

> Marshall Price wrote:
> > Andrew, in the Holy Spirit, wrote in part:
> >
> > > By GOD's design, there is one optimal amount for every adult as
> > > denoted by the Hebrew word "omer" (Exodus 16:16).

> > Why not save us the trouble of looking it up?

>
> "Each one is to gather as much as he needs. Take an omer for each
> person you have in your tent." -- LORD Almighty GOD (Exodus 16:16)
>
> 16 + 16 = 32
>
> Reminding us that the one optimal amount is 32 ounces.


Huh?

You take the numbers from the chapter and verse? But those aren't in
the original. Then you add them together? Why? Why "ounces"?
"Optimal amount" of what? Manna? Per day?

An omer is a tenth of an ephah, which is about a bushel, which is
about 32 quarts, so an omer (as a measure of grain) is about 3.2 quarts.
That's "an optimal amount" for a day?

Why take something God said to the Israelites gathering manna in the
desert (if I recall correctly) as his "design" for "every adult"? And
where are you getting manna, anyway?

--
Marshall Price of Miami
Known to Yahoo as d021317c
  #107  
Old 05-19-2008, 12:50 AM
Bob Arnold
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

In article <-5mdnfjWNLwkbbLVnZ2dnUVZ_tHinZ2d[at]earthlink.com> ,
Marshall Price <d021317c[at]yahoo.com> wrote:

- quote -

> jay wrote:
> > > > What supplements provide relief from polyneuropathy?
> > > Nobody seems to have mentioned the most obvious one, thiamine!

> >
> > My multi-vitamin says one tablet has 75mg of Thiamine HCl (5000%). Is
> > this too much?

>
> It sounds like too much to me, but many people take that much, or
> more. The multi-vitamin-mineral tablets I take afford about one DV
> (that is, 100%) for each vitamin and mineral, except for the major
> minerals. (For thiamine, that means 1.5mg.)
>
> But I also take a few vitamins "on the side" for specific purposes,
> and I expect to get most of my nutrients from food, not to mention the
> zillions of honored guest symbiotes in my digestive tract. I'd be lost
> without them. ;-)



It's not too much. I take 540mg Thiamine per day.
  #106  
Old 05-18-2008, 07:28 PM
Truth
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

On May 18, 1:31 am, Marshall Price <d0213...[at]yahoo.com> wrote:
- quote -

> Andrew B. Chung, MD/PhD wrote:
>
> > By GOD's design, there is one optimal amount for every adult as
> > denoted by the Hebrew word "omer" (Exodus 16:16).

>
> Why not save us the trouble of looking it up?
>
> --
> Marshall Price of Miami
> Known to Yahoo as d021317c


Chung has been told many times that scholars agree that an omer is a
biblical measure of volume equivalent to approximately 2 liters or
quarts. Yet he is fixated on the fact that the verse mentioning an
omer as being the right amount of food for the Israelites wandering in
the desert is Exodus 16:16. He therefore twists this to be numerology
"proof" that an omer is 2 pounds or 32 ounces.

Chung initially fixated on the 2 pounds per person per day diet when
he saw some IMAX film about Everest climbers and mistakenly came away
with the idea that those climbers ate only 2 pounds of food per day.
As his mental illness progressed and he became more fixated on quasi-
Christianity, this 2 pounds a day morphed from being inspired by the
IMAX Everest film into being inspired by Chung's lone ranger,
idiosyncratic and mistaken interpretation of the biblical measure of
volume, an omer.

Chung is a disgraced ex-cardiologist who lost his first post-
cardiology fellowship job in Ocala, Florida in about 3 months and has
not worked since. He is a pathological, regressed narcissist and a
known Usenet k00k and a pathological liar.

Respond to his posts for amusement value only. Nothing that he says is
evidence-based.
  #105  
Old 05-18-2008, 09:02 AM
Marshall Price
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

jay wrote:
- quote -

> > > What supplements provide relief from polyneuropathy?
> > Nobody seems to have mentioned the most obvious one, thiamine!

>
> My multi-vitamin says one tablet has 75mg of Thiamine HCl (5000%). Is
> this too much?


It sounds like too much to me, but many people take that much, or
more. The multi-vitamin-mineral tablets I take afford about one DV
(that is, 100%) for each vitamin and mineral, except for the major
minerals. (For thiamine, that means 1.5mg.)

But I also take a few vitamins "on the side" for specific purposes,
and I expect to get most of my nutrients from food, not to mention the
zillions of honored guest symbiotes in my digestive tract. I'd be lost
without them. ;-)

--
Marshall Price of Miami
Known to Yahoo as d021317c
  #104  
Old 05-18-2008, 09:01 AM
Andrew B. Chung, MD/PhD
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

Marshall Price wrote:
- quote -

> Andrew, in the Holy Spirit, wrote in part:
>
> > By GOD's design, there is one optimal amount for every adult as
> > denoted by the Hebrew word "omer" (Exodus 16:16).

>
> Why not save us the trouble of looking it up?


"Each one is to gather as much as he needs. Take an omer for each
person you have in your tent." -- LORD Almighty GOD (Exodus 16:16)

16 + 16 = 32

Reminding us that the one optimal amount is 32 ounces.

Be hungry... be healthy... be hungrier... be euglycemic...

Prayerfully in the awesome name of LORD Jesus Christ,

Andrew <> <
--
http://groups.google.com/group/sci.m...8812d72ab4e17?
  #103  
Old 05-18-2008, 08:56 AM
Andrew B. Chung, MD/PhD
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

Marshall Price wrote:
- quote -

> Andrew, in the Holy Spirit, boldly wrote:
> > friend jay wrote:
> > > > Be hungry... be healthy... be hungrier... be healthier...
> > > Good advice. I try to fast on Sundays.
> > >
> > > The formation of peripheral myelin protein 22 aggregates is hindered
> > > by the enhancement of autophagy and expression of cytoplasmic
> > > chaperones.
> > >
> > > The accumulation of misfolded proteins is associated with various
> > > neurodegenerative conditions. Peripheral myelin protein 22 (PMP22) is
> > > a hereditary neuropathy-linked, short-lived molecule that forms
> > > aggresomes when the proteasome is inhibited or the protein is mutated.
> > > We previously showed that the removal of pre-existing PMP22 aggregates
> > > is assisted by autophagy. Here we examined whether the accumulation of
> > > such aggregates could be suppressed by experimental induction of
> > > autophagy and/or chaperones. Enhancement of autophagy during
> > > proteasome inhibition hinders protein aggregate formation and
> > > correlates with a reduction in accumulated proteasome substrates.
> > > Conversely, simultaneous inhibition of autophagy and the proteasome
> > > augments the formation of aggregates. An increase of heat shock
> > > protein levels by geldanamycin treatment or heat shock preconditioning
> > > similarly hampers aggresome formation. The beneficial effects of
> > > autophagy and chaperones in preventing the accumulation of misfolded
> > > PMP22 are additive and provide a potential avenue for therapeutic
> > > approaches in hereditary neuropathies linked to PMP22 mutations. PMID:
> > > 17174099

> >
> > Fasting can result in hyperketonemia, which suppresses hunger.
> >
> > It is only when we are hungrier, that our bodies "burn" away the VAT
> > (black fat):
> >
> > http://groups.google.com/group/sci.m...8812d72ab4e17?

>
> Those links don't mention "VAT" or "black."


http://groups.google.com/group/sci.m...e435e3ec529db?

Be hungry... be healthy... be hungrier... be euglycemic...

Prayerfully in the awesome name of LORD Jesus Christ,

Andrew <> <
--
http://groups.google.com/group/sci.m...8812d72ab4e17?
  #102  
Old 05-18-2008, 08:31 AM
Marshall Price
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

Andrew B. Chung, MD/PhD wrote:
- quote -

> By GOD's design, there is one optimal amount for every adult as
> denoted by the Hebrew word "omer" (Exodus 16:16).


Why not save us the trouble of looking it up?

--
Marshall Price of Miami
Known to Yahoo as d021317c
  #101  
Old 05-18-2008, 08:29 AM
Marshall Price
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

timothytn[at]my-deja.com wrote:
- quote -

> Here is the result of small clinical trials in humans in Germany as of
> 1999. There may be more positive evidence since then. High pyridoxine
> supplementation usually in excess of 600 mg./day has resulted in
> neuropathy in a small number of people. They were taking it for carpal
> tunnel syndrome. They were also taking it w/o other B vitamins and the
> condition was reversible. Personally I have taken 1000 mg/d for
> extended periods w/o side effects. It's probably best to steer clear
> of supplementation IMHO.


Taking large amounts of B6 without extra B2 is a no-no.

--
Marshall Price of Miami
Known to Yahoo as d021317c
  #100  
Old 05-18-2008, 08:23 AM
Marshall Price
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

Andrew B. Chung, MD/PhD wrote:
- quote -

> friend jay wrote:
> > > Be hungry... be healthy... be hungrier... be healthier...

> > Good advice. I try to fast on Sundays.
> >
> > The formation of peripheral myelin protein 22 aggregates is hindered
> > by the enhancement of autophagy and expression of cytoplasmic
> > chaperones.
> >
> > The accumulation of misfolded proteins is associated with various
> > neurodegenerative conditions. Peripheral myelin protein 22 (PMP22) is
> > a hereditary neuropathy-linked, short-lived molecule that forms
> > aggresomes when the proteasome is inhibited or the protein is mutated.
> > We previously showed that the removal of pre-existing PMP22 aggregates
> > is assisted by autophagy. Here we examined whether the accumulation of
> > such aggregates could be suppressed by experimental induction of
> > autophagy and/or chaperones. Enhancement of autophagy during
> > proteasome inhibition hinders protein aggregate formation and
> > correlates with a reduction in accumulated proteasome substrates.
> > Conversely, simultaneous inhibition of autophagy and the proteasome
> > augments the formation of aggregates. An increase of heat shock
> > protein levels by geldanamycin treatment or heat shock preconditioning
> > similarly hampers aggresome formation. The beneficial effects of
> > autophagy and chaperones in preventing the accumulation of misfolded
> > PMP22 are additive and provide a potential avenue for therapeutic
> > approaches in hereditary neuropathies linked to PMP22 mutations. PMID:
> > 17174099

>
> Fasting can result in hyperketonemia, which suppresses hunger.
>
> It is only when we are hungrier, that our bodies "burn" away the VAT
> (black fat):
>
> http://groups.google.com/group/sci.m...8812d72ab4e17?
>
> Prayerfully in the awesome name of LORD Jesus Christ,
>
> Andrew <> <
> --
> http://groups.google.com/group/sci.m...50caf5f7c3989?


Those links don't mention "VAT" or "black."

Also, are you aware of the fact that when "lord" is written in upper
case, that signals that it is being used as a substitute for the
tetragrammaton? "LORD Jesus Christ" is entirely different from "Lord
Jesus Christ," and it seems to imply that the author opposes the
doctrine of the trinity.

"KING," on the other hand, means nothing, except that the author
enjoys flouting typographical conventions.

--
Marshall Price of Miami
Known to Yahoo as d021317c
  #99  
Old 05-18-2008, 08:19 AM
Andrew B. Chung, MD/PhD
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

Marshall Price wrote:
- quote -

> Andrew, in the Holy Spirit, boldly wrote:
> > jay wrote:
> > > What supplements provide relief from polyneuropathy? Would the
> > > following be the most important? Already doing paleo-type diet,
> > > moderate exercise and multi-vitamins.
> > >
> > > Benfotiamine
> > > Vitamin B6 (P-5-P)
> > > R-Lipoic Acid
> > > NAC
> > > Acetyl-L-Carnitine

> >
> > In our collective clinical experience, no supplement(s) can overcome
> > the deleterious effect that PIACs from VAT (black fat) has on the
> > fragile efferent fibers of sensory neurons thereby causing the
> > peripheral neuropathy.

>
> What are PIACs?


Pro-Inflammatory AdipoCytokines

Be hungry... be healthy... be hungrier... be euglycemic...

Prayerfully in the awesome name of LORD Jesus Christ,

Andrew <> <
--
http://groups.google.com/group/sci.m...8812d72ab4e17?
  #98  
Old 05-18-2008, 08:06 AM
Marshall Price
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

Andrew B. Chung, MD/PhD wrote:
- quote -

> jay wrote:
> > What supplements provide relief from polyneuropathy? Would the
> > following be the most important? Already doing paleo-type diet,
> > moderate exercise and multi-vitamins.
> >
> > Benfotiamine
> > Vitamin B6 (P-5-P)
> > R-Lipoic Acid
> > NAC
> > Acetyl-L-Carnitine

>
> In our collective clinical experience, no supplement(s) can overcome
> the deleterious effect that PIACs from VAT (black fat) has on the
> fragile efferent fibers of sensory neurons thereby causing the
> peripheral neuropathy.


What are PIACs?

--
Marshall Price of Miami
Known to Yahoo as d021317c
  #97  
Old 05-18-2008, 08:03 AM
Marshall Price
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

Tiger_Lily wrote:
- quote -

> jay wrote:
> > > take a look at ..... www.diabetic-talk.org/dpn.htm

> > Thanks. They recommends a cocktail of slow-released Lipoic Acid, EPO
> > and Vitamin C. Is the reason why EPO helps neuropathy well
> > established? Is the below related?

>
> i don't know the details, i didn't write the article, nor do the
> research for it
>
> i DO KNOW 6 or 7 diabetics who no longer have the tingling/burning/socks
> under the toes feelings that they used to have
>
> good bg control is imperative as well....
>


That burning-foot problem might be related to circulatory, not
neurological, trouble. I had that symptom when my cholesterol was high.

Adele Davis recommended pantothenic acid (vitamin B5) for burning
feet, which didn't help me. But pantethine, which is closely related to
it, is among the three B vitamins, including niacin (vitamin B3) and
pyridoxine (vitamin B6), which definitely do lower LDL cholesterol. (I
don't know much about pantethine, but pantothenic acid works the same
way, costs much less, and is almost as effective.)

And I ate two to six cups of cooked oat bran every day, which also
has been proven to work.

The peripheral neuropathy I cleared up by taking thiamine (vitamin
B1) was different. It showed up as a small area of numbness on the
medial aspect of my right big toe -- and it went away fast, probably
because I reacted quickly.

In any case, losing one third of my weight by fasting seems to have
solved both problems permanently for me -- and not only did it cost
nothing, but it actually saved me my food budget for six weeks!


--
Marshall Price of Miami
Known to Yahoo as d021317c
  #96  
Old 05-17-2008, 09:42 AM
trigonometry1972@gmail.com |
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

On May 16, 4:39*pm, jay <jaym1...[at]hotmail.com> wrote:
- quote -

> > > What supplements provide relief from polyneuropathy?
>
> > *Nobody seems to have mentioned the most obvious one, thiamine!

>
> My multi-vitamin says one tablet has 75mg of Thiamine HCl (5000%). Is
> this too much?


Naw, there is research comparing benforiamine and thiamine
and the doses needed of thiamine were 10 to 15 times that
for a modest competative response. The benfotiamine
was more effective at lower dose. As I recall the
therapeutic dose of benfotiamine was 300 milligrams.

Huge numbers take 50 to 100 mg of thiamine daily and
people aren't dying in the streets.

With all B-vitamins one is well advised to take not one
vitamin but all the B-vitamins and even some magnesium
during the day. A high level one can increase
the need for higher levels of some of the others.
I recently say article on this point having to
do with folic acid and cobalamin. And I've
read this comment about thiamine and the other Bs,
and B-6 and magnesium as examples.

This is also true with the fat soluble vitamins.
If one takes E then one should take K.
If one takes D then one should take K.
If one takes A then one should likely take D.
If one take A one should also take E.
If one take alpha tocopherol then one
should take gamma tocopherol and the others as well.
And I suppose a mixture of K1 and K2 will
likely have some merits.

And most multi vitamins just don't cut especially
the most massively marketed ones i.e. One a Day,
Centrum and their ilk.
  #95  
Old 05-16-2008, 11:39 PM
jay
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

- quote -

> > What supplements provide relief from polyneuropathy?
>
> *Nobody seems to have mentioned the most obvious one, thiamine!


My multi-vitamin says one tablet has 75mg of Thiamine HCl (5000%). Is
this too much?
  #94  
Old 05-16-2008, 10:12 PM
Nicky
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

On Fri, 16 May 2008 17:40:01 -0400, Marshall Price
<d021317c[at]yahoo.com> wrote:

- quote -

> jay wrote:
> > What supplements provide relief from polyneuropathy? Would the
> > following be the most important? Already doing paleo-type diet,
> > moderate exercise and multi-vitamins.
> >
> > Benfotiamine
> > Vitamin B6 (P-5-P)
> > R-Lipoic Acid
> > NAC
> > Acetyl-L-Carnitine

>
> Nobody seems to have mentioned the most obvious one, thiamine!


Benfotiamine is a better source than thiamine, it's got more
absorption sites.

Nicky.
T2 dx 05/04 + underactive thyroid
D&E, 100ug thyroxine
Last A1c 5.6% BMI 25
  #93  
Old 05-16-2008, 09:55 PM
Andrew B. Chung, MD/PhD
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

timoth...[at]my-deja.com wrote:
- quote -

>
> Here is the result of small clinical trials in humans in Germany as of
> 1999. There may be more positive evidence since then. High pyridoxine
> supplementation usually in excess of 600 mg./day has resulted in
> neuropathy in a small number of people. They were taking it for carpal
> tunnel syndrome. They were also taking it w/o other B vitamins and the
> condition was reversible. Personally I have taken 1000 mg/d for
> extended periods w/o side effects. It's probably best to steer clear
> of supplementation IMHO.


A GI tract including its bacterial flora that is processing an optimal
amount of food each day is one that is capable, with GOD's blessing,
of extracting and supplying the required nutrients (macro, micro, and
trace) in a precisely regulated fashion to meet the specific highly
variable requirements of the body.

By GOD's design, there is one optimal amount for every adult as
denoted by the Hebrew word "omer" (Exodus 16:16).

Have been eating HIS optimal amount since 1997 so that I can
personally testify that GOD is absolutely right in HIS design.

Laus Deo ! ! !

Be hungry... be healthy... be hungrier... be euglycemic...

Prayerfully in the awesome name of LORD Jesus Christ,

Andrew <> <
--
http://groups.google.com/group/sci.m...8812d72ab4e17?
  #92  
Old 05-16-2008, 09:40 PM
Marshall Price
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

jay wrote:
- quote -

> What supplements provide relief from polyneuropathy? Would the
> following be the most important? Already doing paleo-type diet,
> moderate exercise and multi-vitamins.
>
> Benfotiamine
> Vitamin B6 (P-5-P)
> R-Lipoic Acid
> NAC
> Acetyl-L-Carnitine


Nobody seems to have mentioned the most obvious one, thiamine!

--
Marshall Price of Miami
Known to Yahoo as d021317c
  #91  
Old 05-16-2008, 08:32 PM
timothytn@my-deja.com
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

Here is the result of small clinical trials in humans in Germany as of
1999. There may be more positive evidence since then. High pyridoxine
supplementation usually in excess of 600 mg./day has resulted in
neuropathy in a small number of people. They were taking it for carpal
tunnel syndrome. They were also taking it w/o other B vitamins and the
condition was reversible. Personally I have taken 1000 mg/d for
extended periods w/o side effects. It's probably best to steer clear
of supplementation IMHO.

Exp Clin Endocrinol Diabetes. 1999;107(7):421-30.Links
Alpha-lipoic acid in the treatment of diabetic polyneuropathy in
Germany: current evidence from clinical trials.Ziegler D, Reljanovic
M, Mehnert H, Gries FA.
Diabetes-Forschungsinstitut an der Heinrich-Heine-Universität,
Düsseldorf, Germany. dan.ziegler[at]dfi.uni-duesseldorf.de

Diabetic neuropathy represents a major health problem, as it is
responsible for substantial morbidity, increased mortality, and
impaired quality of life. Near-normoglycaemia is now generally
accepted as the primary approach to prevention of diabetic neuropathy,
but is not achievable in a considerable number of patients. In the
past two decades several medical treatments that exert their effects
despite hyperglycaemia have been derived from the experimental
pathogenetic concepts of diabetic neuropathy. Such compounds have been
designed to improve or slow the progression of the neuropathic process
and are being evaluated in clinical trials, but with the exception of
alpha-lipoic acid (thioctic acid) which is available in Germany, none
of these drugs is currently available in clinical practice. Here we
review the current evidence from the clinical trials that assessed the
therapeutic efficacy and safety of thioctic acid in diabetic
polyneuropathy. Thus far, 15 clinical trials have been completed using
different study designs, durations of treatment, doses, sample sizes,
and patient populations. Within this variety of clinical trials, those
with beneficial effects of thioctic acid on either neuropathic
symptoms and deficits due to polyneuropathy or reduced heart rate
variability resulting from cardiac autonomic neuropathy used doses of
at least 600 mg per day. The following conclusions can be drawn from
the recent controlled clinical trials. 1.) Short-term treatment for 3
weeks using 600 mg of thioctic acid i.v. per day appears to reduce the
chief symptoms of diabetic polyneuropathy. A 3-week pilot study of
1800 mg per day given orally indicates that the therapeutic effect may
be independent of the route of administration, but this needs to be
confirmed in a larger sample size. 2.) The effect on symptoms is
accompanied by an improvement of neuropathic deficits. 3.) Oral
treatment for 4-7 months tends to reduce neuropathic deficits and
improves cardiac autonomic neuropathy. 4.) Preliminary data over 2
years indicate possible long-term improvement in motor and sensory
nerve conduction in the lower limbs. 5.) Clinical and postmarketing
surveillance studies have revealed a highly favourable safety profile
of the drug. Based on these findings, a pivotal long-term multicenter
trial of oral treatment with thioctic acid (NATHAN I Study) is being
conducted in North America and Europe aimed at slowing the progression
of diabetic polyneuropathy using a clinically meaningful and reliable
primary outcome measure that combines clinical and neurophysiological
assessment.

PMID: 10595592 [PubMed - indexed for MEDLINE]
  #90  
Old 05-16-2008, 08:15 PM
Andrew B. Chung, MD/PhD
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

friend jay wrote:
- quote -

>
> > Be hungry... be healthy... be hungrier... be healthier...

>
> Good advice. I try to fast on Sundays.
>
> The formation of peripheral myelin protein 22 aggregates is hindered
> by the enhancement of autophagy and expression of cytoplasmic
> chaperones.
>
> The accumulation of misfolded proteins is associated with various
> neurodegenerative conditions. Peripheral myelin protein 22 (PMP22) is
> a hereditary neuropathy-linked, short-lived molecule that forms
> aggresomes when the proteasome is inhibited or the protein is mutated.
> We previously showed that the removal of pre-existing PMP22 aggregates
> is assisted by autophagy. Here we examined whether the accumulation of
> such aggregates could be suppressed by experimental induction of
> autophagy and/or chaperones. Enhancement of autophagy during
> proteasome inhibition hinders protein aggregate formation and
> correlates with a reduction in accumulated proteasome substrates.
> Conversely, simultaneous inhibition of autophagy and the proteasome
> augments the formation of aggregates. An increase of heat shock
> protein levels by geldanamycin treatment or heat shock preconditioning
> similarly hampers aggresome formation. The beneficial effects of
> autophagy and chaperones in preventing the accumulation of misfolded
> PMP22 are additive and provide a potential avenue for therapeutic
> approaches in hereditary neuropathies linked to PMP22 mutations. PMID:
> 17174099


Fasting can result in hyperketonemia, which suppresses hunger.

It is only when we are hungrier, that our bodies "burn" away the VAT
(black fat):

http://groups.google.com/group/sci.m...8812d72ab4e17?

Prayerfully in the awesome name of LORD Jesus Christ,

Andrew <> <
--
http://groups.google.com/group/sci.m...50caf5f7c3989?
  #89  
Old 05-16-2008, 08:03 PM
jay
Guest
 
Posts: n/a
Default Re: Supplements for Neuropathy

- quote -

> Be hungry... be healthy... be hungrier... be healthier...

Good advice. I try to fast on Sundays.

The formation of peripheral myelin protein 22 aggregates is hindered
by the enhancement of autophagy and expression of cytoplasmic
chaperones.

The accumulation of misfolded proteins is associated with various
neurodegenerative conditions. Peripheral myelin protein 22 (PMP22) is
a hereditary neuropathy-linked, short-lived molecule that forms
aggresomes when the proteasome is inhibited or the protein is mutated.
We previously showed that the removal of pre-existing PMP22 aggregates
is assisted by autophagy. Here we examined whether the accumulation of
such aggregates could be suppressed by experimental induction of
autophagy and/or chaperones. Enhancement of autophagy during
proteasome inhibition hinders protein aggregate formation and
correlates with a reduction in accumulated proteasome substrates.
Conversely, simultaneous inhibition of autophagy and the proteasome
augments the formation of aggregates. An increase of heat shock
protein levels by geldanamycin treatment or heat shock preconditioning
similarly hampers aggresome formation. The beneficial effects of
autophagy and chaperones in preventing the accumulation of misfolded
PMP22 are additive and provide a potential avenue for therapeutic
approaches in hereditary neuropathies linked to PMP22 mutations. PMID:
17174099
 

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neuropathy, supplements
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Kamalakar Pasupuleti: I mentioned in my previous post about the neuro specialist prescribing me Elavil 25 mg at bedtime for tingling of soles , my PCP had recommended Vitamin B 12 250 mcg once a day . I was advised to go thru bone density test which revealed I was...
Kamalakar Pasupuleti Nutrition 3 09-30-2005 12:07 PM
Methylcobalamimin and Diabetic Neuropathy
Kamalakar Pasupuleti: I understand Methylcobalamin is good for diabetic peripheral neuropathy . The product is available in health food /vitamin stores only for reasons not known to me . I welcome feedback from it's users . I wish to try for my tingling of soles ....
Kamalakar Pasupuleti Nutrition 3 09-24-2005 11:46 AM
LIFE UNDER CODEX - taking away supplements, then profiteering from supplements of lower value
john: LIFE UNDER CODEX By Helke Ferrie Vitality Magazine February 2005 It is not the function of our Government to keep the citizen from falling into error; it is the function of the citizen to keep the Government from falling into error.
john Nutrition 153 05-07-2005 07:28 AM
Neuropathy from extreme diet, sound possible??
fgt@aol.com: Due to mystery illness, I started avoiding carbs, and went to almost vegen diet for weeks. Then I added some meats, but basically stayed away from milk/dairy/ breads/ sugars and lived on mostly meats and vegetables. I took many supplements....
fgt@aol.com Nutrition 10 02-12-2005 10:11 AM



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