On Jun 9, 7:53 am, "ironjust...[at]aol.com" <ironjust...[at]aol.com> wrote:
Role of iron in type 2 diabetes <<

"Phlebotomy Successfully Treats Cardiomyopathy"
------ "Tissue stains from a heart biopsy showed an extremely high level of
iron which was the cause of his cardiomyopathy that led to congestive
heart failure.
Diagnosis was hereditary hemochromatosis leading to diabetes and
cardiomyopathy."
http://tinyurl.com/3zh3et
------
"Phlebotomy Successfully Treats Cardiomyopathy"

Internist (Berl). 2008 Jan 23 [Epub ahead of print] Links
[28-year old patient with successfully treated dilatative
cardiomyopathy.][Article in German]

Burri E, Decker M, Eriksson U, Buser P, Hunziker L.
Innere Medizin, Universitätsspital Basel, Petersgraben 4, 4031,
Basel,
Schweiz, Bur...[at]uhbs.ch.


A 28-year was admitted with heart failure. His medical history
included treatment for hypogonadotropic hypogonadism.
Echocardiography
showed dilatation of all chambers. Elevated serum ferritin levels and
liver biopsy indicated hereditary hemochromatosis. Cardiac iron
overload was seen on magnetic resonance imaging. Genetic testing
revealed homozygosis for G320 V mutation, confirming the diagnosis of
juvenile hemochromatosis. Phlebotomy on a biweekly regimen was
started
and after twelve months of therapy the patient had normal ferritin
values as well as normal ejection fraction on echocardiography.


PMID: 18210019 [PubMed - as supplied by publisher]


Who loves ya.
Tom


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- quote -

The role of iron in type 2 diabetes in humans.
Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB
Biochim Biophys Acta 2008 May 3.

The role of micronutrients in the etiology of type 2 diabetes is not
well studied.
Several lines of evidence suggest that iron may a role in the
pathogenesis of type 2 diabetes.
Iron is a strong pro-oxidant and high body iron levels are associated
with increased level of oxidative stress that may elevate the risk of
type 2 diabetes.
Several epidemiological studies have reported a positive association
between high body iron levels, as measured by circulating ferritin
level, and the risk of type 2 diabetes and of other insulin resistance
states such as the metabolic syndrome, gestational diabetes and
polycystic ovarian syndrome.
In addition, increased dietary intake of iron, especially that of heme
iron, is associated with risk of type 2 diabetes in apparently healthy
populations.
Results from studies that evaluated the association between genetic
mutations related to iron metabolism have been inconsistent.
Further, several clinical trials suggest that by phlebotomy induced
reduction in body iron levels may improve insulin sensitivity in
humans.
However, no interventional studies have yet directly evaluated the
effect of reducing iron intake or body iron levels on the risk of
developing type 2 diabetes.
Such studies are required to prove the causal relationship between
moderate iron overload and diabetes risk.
Biochimica et biophysica acta [Biochim Biophys Acta]
------------------------------------------------

Who loves ya.
Tom


Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk